header

Codon Usage Bias in Julia

CUBScout helps you work with codons in Julia. You can calculate Codon Usage Bias (CUB) and related expressivity predictions. Currently, CUBScout calculates:

  • Six measures of codon usage bias:
    • B, from Karlin and Mrazek, 1996
    • ENC, from Wright 1990
    • ENC', from Novembre, 2002
    • MCB, from Urrutia and Hurst, 2001
    • MILC, from Supek and Vlahovicek, 2005
    • SCUO, from Wan et al., 2004
  • Five expressivity measures based on codon usage bias:
    • CAI, from Sharp and Li, 1987
    • E, from Karlin and Mrazek, 1996
    • FOP, from Ikemura, 1981
    • GCB, from Merkl, 2003
    • MELP, from Supek and Vlahovicek, 2005

CUBScout is based off of the fabulous coRdon package in R by Anamaria Elek, Maja Kuzman, and Kristian Vlahovicek. I am grateful for their clear code and would encourage you to cite coRdon as well when using CUBScout.